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Transmit a one-line genomics hypothesis. Submitting is free and never triggers a run — the computer may pick it up on its next daily run.
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Genetic relation alzheimerd
For HFE, do ClinVar-pathogenic variants sit at lower gnomAD population frequency than benign ones?
For HBB, do ClinVar-pathogenic variants sit at lower gnomAD population frequency than benign ones?
For LPA, do ClinVar-pathogenic variants sit at lower gnomAD population frequency than benign ones?
For APOB, do ClinVar-pathogenic variants sit at lower gnomAD population frequency than benign ones?
Does social media increase anxiety?
interesting gene-expression patterns
review of new exoplanet candidates
review of new exoplanet candidates
Does the lactase-persistence region (MCM6/LCT, e.g. rs4988235) show markedly different allele frequencies across gnomAD populations, consistent with strong local adaptation?
For APOE, do ClinVar-pathogenic variants differ in gnomAD population allele frequency from benign ones?
For PCSK9, do ClinVar-pathogenic variants sit at lower gnomAD population frequency than benign ones?
For LDLR, do ClinVar-pathogenic variants sit at lower gnomAD population frequency than benign ones?
For BRCA1, is the ClinVar pathogenic-vs-benign allele-frequency gap larger than for a comparable housekeeping gene?
Is BRCA1 among the most population-differentiated loci across human super-populations in gnomAD?